Professor Svetlana Villevalde presented the results of the use of a new selective cardiac myosin activator - omecamtiva mecarbil in the international multicenter randomized placebo-controlled study GALACTICA-HF. In a severe cohort of patients with HF and left ventricular ejection fraction less than 35% and additional factors such as hypotension, recent hospitalization, high levels of NT-proBNP, the use of omecamtiv mecarbil affected the increase in myocardial contractility, significantly reducing the risk of repeated hospitalizations for HF and death [odds ratio 0.92; 95% confidence interval [0.86-0.99], p=0.03] compared to patients taking placebo [3].

With a very interesting report "Artificial intelligence in medicine: progress or threat?» Professor Martin Cowie (Great Britain) made a speech. Martin Cowie believes that artificial intelligence with the help of algorithms and processes of prediction and classification can help a person to anticipate certain clinical moments, process huge arrays of databases and identify patient phenotypes, make high-quality decisions in a short time. Areas of science and practice where artificial intelligence is already used were presented: visualization techniques, metobiomics, genomics, diagnostics and classification.

Corresponding member of the Russian Academy of Sciences, Alexandra Konradi, in her clear and highly professional report on e-health, highlighted the main features of the organization of medical care in the Russian Federation and the changes in the degree of patient involvement in treatment as a result of increasing their medical awareness. It was also possible to discuss the existing complexities of e-health: organization of work, data protection, training of specialists, and, of course, possible sources of funding. Despite these small nuances, at the moment, clinics are actively introducing and successfully operating systems for registering patients for appointments and other telemedicine technologies.

Professor Cecilia Linde presented the latest clinical recommendations for the treatment of atrial fibrillation, focusing on the role of modern algorithms and physiological pacing.

During the discussion of the morning session, Corresponding member of the Russian Academy of Sciences Simon Matskeplishvili made a short presentation, recalling the pathophysiology of the circulatory system in the aspect of echocardiographic diagnostics and drug treatment of patients with CHF. Such messages help to develop the clinical thinking of the doctor, as well as teach the choice of a patient-oriented treatment strategy in the context of the emergence of new drugs.

We thank the co-chairs of the Forum, Academician of the Russian Academy of Sciences, President of the Russian Society of Cardiology - Evgeny Vladimirovich Shlyakhto and Professor Michel Komajda for such a rich and versatile program!

All the knowledge gained during the forum will continue to spread throughout the Russian Federation for the benefit of our patients lives!

We would like to express my deep gratitude to the leadership of the Russian Cardiological Society for the excellently organized event and the much-needed support for young cardiologists in Russia to participate in this international Forum.

We thank the working group of young cardiologists for their activity and commitment to the implementation of new plans! We are proud to be a part of the Russian Society of Cardiology!

 

References:

  1. Armstrong PW, Pieske B, Anstrom KJ,et al. VICTORIA Study Group. Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction. N Engl J Med. 2020;382(20):1883-1893. doi: 10.1056/NEJMoa1915928.
  2. Zannad F, Ferreira JP, Pocock SJ, et al. SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials. Lancet. 2020;396(10254):819-829. doi: 10.1016/S0140-6736(20)31824-9.
  3. Teerlink JR, Diaz R, Felker GM et al. GALACTIC-HF Investigators. Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure. N Engl J Med. 2021 Jan 14;384(2):105-116. doi: 10.1056/NEJMoa2025797. Epub 2020 Nov 13. PMID: 33185990.

 

   

Contacts:

Lyapina Irina, e-mail: zaviirina@mail.ru

 

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