In women treated for early breast cancer, the angiotensin receptor blocker candesartan protected against a decline in left ventricular ejection fraction, but the beta-blocker metoprolol did not, researchers reported here.
Patients with atrial fibrillation who received the novel antiarrthyhmic drug vernakalant had faster conversion time to sinus rhythm and greater conversion success than patients assigned ibutilide.
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The most frequent causes of ticagrelor discontinuation in the PEGASUS?TIMI 54 study were dyspnea and bleeding, and many of those events were minor, according to results of a substudy presented at the American Heart Association Scientific Sessions.
The announcement was based on a review of the Dual Antiplatelet Therapy (DAPT) trial, as well as of other large clinical trials that also examined adverse events from clopidogrel use.
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