Stroke and Major Bleeding Risk in Elderly Patients Aged ?75 Years With Atrial Fibrillation: The Loire Valley Atrial Fibrillation Project

12.12.20141782
What are the risks of stroke and bleeding in elderly patients with atrial fibrillation (AF) associated with oral anticoagulation?

Opportunities for treatment optimization with beta-blockers, ivabradine often missed in HF clinic

11.12.20141558
Most HF patients with reduced ejection fraction treated at a community HF clinic received beta-blocker therapy to maintain a heart rate <70 bpm, but relatively few require beta-blocker up-titration or ivabradine initiation, results of a new study suggest.

Recent Cox-2 inhibitor use increased ischemic stroke mortality risk

10.12.20141366
The use of cyclooxygenase-2 inhibitors before hospitalization for stroke is associated with increased mortality in cases of ischemic stroke, but not hemorrhagic stroke, according to recent findings.

Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis

08.12.20141543
Experimental data indicate that reducing factor XI levels attenuates thrombosis without causing bleeding, but the role of factor XI in the prevention of postoperative venous thrombosis in humans is unknown. FXI-ASO (ISIS 416858) is a second-generation antisense oligonucleotide that specifically reduces factor XI levels.

Aggressive Risk Factor Reduction Study for Atrial Fibrillation and Implications for the Outcome of Ablation: The ARREST-AF Cohort Study

05.12.20141609
Does aggressive risk factor management (RFM) improve outcomes after catheter ablation of atrial fibrillation (AF)?

Noncardiac Comorbidities in Heart Failure With Reduced Versus Preserved Ejection Fraction

04.12.20141844
What are the comorbidities associated with heart failure with preserved ejection fraction (HFpEF) versus heart failure with reduced ejection fraction (HFrEF)?

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03.12.20142224
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