Nonalcoholic fatty liver disease (NAFLD) is closely correlated with insulin resistance and several metabolic syndrome features, but whether it could increase the risk of cardiovascular disease remains undefined.
Strikingly wide variation among patients in plasma levels of atorvastatin and rosuvastatin (Crestor, AstraZeneca), even with consistent dosing, is likely related to gene variants that affect the drugs' uptake by the liver in some patients, suggests a prospective study.
The first aim was to critically evaluate the extent to which familial hypercholesterolaemia (FH) is underdiagnosed and undertreated. The second aim was to provide guidance for screening and treatment of FH, in order to prevent coronary heart disease (CHD).
Rheumatoid arthritis (RA) was associated with a significantly increased risk for potentially fatal blood clots in the legs and lung in a nationwide prospective cohort study from Taiwan published online August 7, 2013 in the Annals of the Rheumatic Diseases.
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