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The most frequent causes of ticagrelor discontinuation in the PEGASUS?TIMI 54 study were dyspnea and bleeding, and many of those events were minor, according to results of a substudy presented at the American Heart Association Scientific Sessions.
The announcement was based on a review of the Dual Antiplatelet Therapy (DAPT) trial, as well as of other large clinical trials that also examined adverse events from clopidogrel use.
The use of macrolide antibiotics may be associated with a minor increase in the risk for sudden cardiac death or ventricular tachyarrhythmias, according to the results of a recently published meta-analysis.
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